Romelu Lukaku and Marcus Rashford scored in quick succession to ensure that United came from behind to beat CSKA Moscow at Old Trafford – as Jose Mourinho took a pre-derby swipe at Pep Guardiola.
Manchester United qualified for the last 16 as Group A winners.
The United’s manager had an eye on the weekend’s derby with his team selection proving so.
Goalkeeper David de Gea, Ashley Young and Jesse Lingard were all rested for the Champions League clash, while Anthony Martial made a late cameo.
Attention has now switched to Sunday’s derby clash with Manchester City; a game United need not to win to reduce the eight point advantage their neighbours have on them.
However, Mourinho took time to accuse Guardiola of employing mind games before the showdown.
Guardiola said David Silva is a doubt for Sunday, but Mourinho suggested the City boss was trying to trick him – just like Arsene Wenger, who claimed Alexandre Lacazette had no chance of facing United – only for him to start and even scored.
Asked about United’s injuries, Mourinho said: “You want the truth? What do you want?
“Eric Bailly has no chance for the weekend, Phil Jones a chance. Marouane Fellaini a chance, Zlatan a big chance.
“Nemanja Matic is injured but will play for sure. I’m telling the truth! It’s the truth. No stories of Lacazatte or David Silva. All the truth.
“Our opponents have all these issues. They have a big issue but, in the end, everybody is ready to play.
“They have phenomenal organisations. We are a bit more humble.
“When we have a problem, we have a problem. When players are injured, they are injured. I tell you the truth.”
United, who made it a club record-equalling 40 home games unbeaten in all competitions, could face Real Madrid, Bayern Munich or Juventus in the last 16.
Mourinho said: “I’m unlucky in draws but I don’t want to think about it till February.”